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By Paul H. Sugarbaker MD, FACS, FRCS (auth.), Santiago González-Moreno MD, PhD (eds.)

S. González-Moreno (Ed. ) Advances in Peritoneal floor Oncology With forty five Figures in fifty seven Separate Illustrations, 12 in colour and 19 Tables 123 IV Preface Santiago González-Moreno, MD, PhD division of Surgical Oncology Centro Oncológico MD Anderson overseas España Calle Gómez Hemans 2 28033 Madrid Spain sgonzalez@mdanderson. es Library of Congress keep an eye on quantity: 2006937141 ISSN 0080-0015 ISBN 978-3-540-30759-4 Springer Berlin Heidelberg long island This paintings is topic to copyright. All rights are reserved, even if the complete or a part of the cloth is anxious, speci? ?cally the rights of translation, reprinting, reuse of illustrations, recitations, broadcasting, copy on micro? ?lm or in the other means, and garage in information banks. Duplication of this ebook or elements thereof is authorized in basic terms less than the provisions of the German Copyright legislations of September nine, 1965, in its present model, and permission to be used should always be got from Springer-Verlag. Violations are chargeable for prosecution below the German Copyright legislation. Springer is a part of Springer Science+Business Media http//www. springer. com Springer-Verlag Berlin Heidelberg 2007 published in Germany using basic descriptive names, logos, and so on. during this booklet doesn't mean, even within the absence of a speci? ?c sta- ment, that such names are exempt from the appropriate protecting legislation and laws and for this reason loose for common use. Product legal responsibility: The publishers can't warrantly the accuracy of any information regarding dosage and alertness contained during this ebook. In each case the person needs to cost such info by means of consulting the proper literature.

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Int J Oncol 111:349–358D 10. Yonemura Y (1998) Mechanisms of the formation of peritoneal dissemination. In: Yonemura Y, Shoten M (eds) Peritoneal dissemination. Kanazawa, pp 1–46 11. Kawamura T, Endo Y, Yonemura Y et al. (2001) Significance of integrin alpha2/beta1 in peritoneal dissemination of a human gastric cancer xenograft model. Int J Oncol 18:809–815 12. Nishimura S, Chung YS, Yashiro M et al. (1996) Role of alpha 2 beta 1- and alpha 3 beta 1-integrin in the peritoneal implantation of scirrhous gastric carcinoma.

Landry J, Tepper JE, Wood WC, Moulton EO, Koerner F, Sullinger J (1990) Patterns of failure following curative resection of gastric carcinoma. Int J Radiat Oncol Biol Phys 19:1357–1362 30. Burke EC, Karpeh MS Jr, Conlon KC, Brennan MF (1998) Peritoneal lavage cytology in gastric cancer: an independent predictor of outcome. Ann Surg Oncol 5:411–415 31. Suzuki T, Ochiai T, Hayashi H, Nakajima K, Yasumoto A, Hishikawa E, Shimada H, Horiuchi F, Ohki S, Isono K (1999) Importance of positive peritoneal lavage cytology findings in the stage grouping of gastric cancer.

Tumour cell groupings reach the peritoneal surface, typically within a crevice, as seen here, where the mesothelial lining is reflected fl from the gastro-oesophageal adventitia onto adjacent connective tissue. In oesophageal and colorectal cancer, these crevices are the preferential area of serosal involvement 27 difference in the microanatomical structure in these areas, making the serosal surface more prone to penetration by tumour [14]. Macroscopically, serosal involvement can be subtle and a telltale sign is loss of the ‘shiny’ appearance of the serosa, possibly associated with telangiectatic blood vessels.

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